Closed projects

The following list contains previous research and projects of TropNet.

Year beginning	Year end	Research field	Title	Status	New sites requested	PI / contact	Date of research committee vote	Number participants	Study design	Study type	Publications – Journal	Publications – DOI
2022	–	Schistosomiasis	Diagnosis and management of complicated urogenital schistosomiasis: a systematic review of the literature	n/a	n/a	Zammarchi	12/14/2022	n/a	Retrospective	Systematic review
2020	–	Schistosomiasis	Multicentric retrospective analysis of complicated schistosomiasis	Recruitment closed	No	Gobbi/Zammarchi	–		Retrospective	Observational
2010	–	Staphylococci	StaphTrav, http://www.staphtrav.eu/	Recruitment open	Yes	Zanger	–	558	Prospective	Observational	Clin Microbiol Infect. 2015 Jun;21(6):567.e1-10. Clin Microbiol Infect. 2019 Jun;25(6):739-746.	doi: 10.1016/j.cmi.2015.01.016 + 10.1016/j.cmi.2018.09.023
2019	–	Malaria	Retrospective, multicenter and European study comparing epidemiological, clinical and laboratory characteristics among patients with imported Plasmodium falciparum infection versus mixed infection with Plasmodium ovale wallikeri or Plasmodium ovale curtisi and Plasmodium falciparum.	Recruitment open	Yes	Rojo / Cuadros	6/8/2022		Retrospective	Observational
2017	2019	Fever	DOXYCYCLINE RESPONDING ILLNESSES IN RETURNING TRAVELERS WITH UNDIFFERENTIATED NON-MALARIA FEVER: A EUROPEAN MULTICENTER PROSPECTIVE COHORT STUDY	Recruitment closed	No	Camprubí / Muñoz	5/18/2022	347	Prospective	Observational	Journal of Travel Medicine	https://doi.org/10.1093/jtm/taac094
2019	2019	Malaria	Outpatient treatment of imported uncomplicated Plasmodium falciparum malaria: results from a survey among TropNet and GeoSentinel experts for tropical medicine	Recruitment closed	No	Lingscheid / Zoller	3/1/2019	n/a	Cross sectional	n/a	Journal of Travel Medicine	doi: 10.1093/jtm/taaa082
2020	2021	Malaria	Artesunate monotherapy versus artesunate plus quinine combination therapy for treatment of imported severe malaria: a TropNet retrospective cohort study	Recruitment closed	No	Zammarchi	3/1/2021	93	Retrospective	Observational	Infection	https://doi.org/10.1007/s15010-022-01771-5
2020	2022	Mansonella	A large case series of travel-related Mansonella perstans (vector-borne ﬁlarial nematode): a TropNet study in Europe	Recruitment closed	No	Tamarozzi / Gobbi	–	392	Retrospective	Observational	Journal of Travel Medicine, 2022, 1–9	https://doi.org/10.1093/jtm/taac048
2019	2021	Giardiasis	Efficacy and Tolerability of Quinacrine Monotherapy and Albendazole Plus Chloroquine Combination Therapy in Nitroimidazole-Refractory Giardiasis	Recruitment closed	No	Neumayr / Bottieau	–	106	Prospective	Observational	Clinical Infectious Diseases ® 2021;73(8):1517–23	DOI: 10.1093/cid/ciab513
2018	2021	Malaria	Artesunate monotherapy versus artesunate plus quinine combination therapy for treatment of imported severe malaria: a TropNet retrospective cohort study	Recruitment closed	No	Botta / Zammarchi	–	93	Prospective	Observational	Infection	https://doi.org/10.1007/s15010-022-01771-5
2019	2020	Schisto	New Insights on Acute and Chronic Schistosomiasis: Do We Need a Redeﬁnition?	n/a	No	Gobbi	n/a	n/a	n/a	n/a	Trends in Parasitology, August 2020, Vol. 36, No. 8	https://doi.org/10.1016/j.pt.2020.05.009
2016	2018	Malaria	Prospective comparative multi‑centre study on imported Plasmodium ovale wallikeri and Plasmodium ovale curtisi infections	Recruitment closed	No	Rojo-Marcos /Llovo-Taboada	–	79	Prospective	Observational	Malar J (2018) 17:399	https://doi.org/10.1186/s12936‑018‑2544‑6
2016	2019	Malaria	RETROSPECTIVE COMPARATIVE MULTICENTER STUDY OF IMPORTED PLASMODIUM FALCIPARUM MALARIA IN PATIENTS WITH AND WITHOUT DIABETES MELLITUS	Recruitment closed	No	Rojo-Marcos	6/30/2022	46	Retrospective	Observational	Doctoral thesis	–
2016	2018	Loiasis	Comparison of different drug regimens for the treatment of loiasis—A TropNet retrospective study	Recruitment closed	No	Gobbi / Bisoffi	–	238	Retrospective	Observational	PLoS Negl Trop Dis 12(11): e0006917.	https://doi.org/10.1371/journal.pntd.0006917
2015	2017	Schisto	Schistosomiasis in European Travelers and Migrants: Analysis of 14 Years TropNet Surveillance Data	Recruitment closed	No	Lingscheid / Zoller	–	1465	Retrospective	Observational	Am. J. Trop. Med. Hyg., 97(2), 2017, pp. 567–574	doi:10.4269/ajtmh.17-0034
2015	2017	Dengue	Sentinel surveillance of imported dengue via travellers to Europe 2012 to 2014: TropNet data from the DengueTools Research Initiative	Recruitment closed	No	Neumayr / Franco	–	673	Prospective	Observational	Euro Surveill. 2017;22(1):pii=30433.	DOI: http://dx.doi.org/10.2807/1560-7917.ES.2017.22.1.30433
2014	2019	Malaria	SMPS Severe Malaria Pharmacovigilance system	Recruitment closed	No	Kurth / Zoller	–	331	Prospective	Observational	–	–
2010	2016	Malaria	HAEMO-ART study: Hemolysis after Oral Artemisinin Combination Therapy for Uncomplicated Plasmodium falciparum Malaria	Recruitment closed	No	Kurth / Zoller	–	27	Prospective	Observational	Emerging Infectious Diseases www.cdc.gov/eid Vol. 22, No. 8, August 2016	http://dx.doi.org/10.3201/eid2208.151905
2009	2017	Malaria	Severe malaria in Europe: an 8-year multi-centre observational study	Recruitment closed	No	Kurth / Zoller	–	185	Prospective	Observational	Malar J (2017) 16:57	DOI 10.1186/s12936-016-1673-z
2009	2015	Malaria	Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study	Recruitment closed	No	Kurth / Zoller	–	185	Prospective	Observational	Clinical Infectious Diseases® 2015;61(9):1441–4	DOI: 10.1093/cid/civ575
2013	2014	Sarcocystis	Acute Muscular Sarcocystosis: An International Investigation Among Ill Travelers Returning From Tioman Island, Malaysia, 2011–2012	Recruitment closed	No	Esposito / Kozarsky	–	68	Retrospective	Observational	Clinical Infectious Diseases ® 2014;59(10):1401–10	DOI: 10.1093/cid/ciu622

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